Right HeartWise RVAD
SELF-POWERED PATIENT-SPECIFIC HEART PUMP FOR RIGHT HEART FAILURE
After LVAD implantation, up to 35% of patients need support in the right ventricle. Every patient has a different cardiac cycle and needs a specific treatment according to their cardiac rhythm.
We provide an RVAD, self-powered and patient-specific ventricular support for right heart failure patients.
Technological Developments
🎯 Patient-specific software & CE Marked - 15 kids
🎯 In vitro test at top surgical & BME journals
🎯 Two acute large-animal experiments
🎯 Human blood tests of Turbine
HeartWise RVAD:
Self-powered
No controller unit
No need electricity
No worries about charging
No need to carry battery packages
No cables are coming out from the body
Increase the quality of life, mobility of the patient and adapts the daily routine of the patient
Cost-effective
Easy to access
Patient-specific
ACHIEVEMENTS
EIC Transition Grant (2.5M Euro), 2025
GALLERY
PUBLICATIONS
RESEARCH PAPERS
Synchronous PIV measurements of a self-powered blood turbine and pump couple for right ventricle support. Ucak K, Karatas F, Cetinkaya E, Pekkan K. Sci Rep. 2024 Aug 28;14(1):19962. doi: 10.1038/s41598-024-70243-7.
Effect of impeller rotational phase on the FDA blood pump velocity fields. Ucak K, Karatas F, Pekkan K. Artif Organs. 2024 Oct;48(10):1126-1137
Switching the Left and the Right Hearts: A Novel Bi-ventricle Mechanical Support Strategy with Spared Native Single-Ventricle. Şişli E, Yıldırım C, Aka İB, Tuncer ON, Atay Y, Özbaran M, Pekkan K. Ann Biomed Eng. 2023 Dec;51(12):2853-2872.
Mechanical support of pulmonary blood flow as a strategy to support the Norwood circulation-lumped parameter model study. Peer SM, Yildirim C, Desai M, Ramakrishnan K, Sinha P, Jonas R, Yerebakan C, Pekkan K. Eur J Cardiothorac Surg. 2022 Jun 15;62(1):ezac262. doi: 10.1093/ejcts/ezac262.
Hemodynamics of neonatal double lumen cannula malposition. Jamil M, Rezaeimoghaddam M, Cakmak B, Yildiz Y, Rasooli R, Pekkan K, Salihoglu E. Perfusion. 2020 May;35(4):306-315. doi: 10.1177/0267659119874697.
CLINICAL PAPERS
Abdelghani M, Mohey S, Elnahas AM, Elshernouby KA, Muharram M, Gebaly M, Mokhaimar B, Elbadawi M, Diab RA, Abdelshafy M, Soliman O, Attia W., Tricuspid valve and right-heart chamber remodelling in elderly subjects with secondary tricuspid regurgitation, Acta Cardiol. 2024 May 31:1-10. doi: 10.1080/00015385.2024.2359657.
Rajapreyar I, Soliman O, Brailovsky Y, Tedford RJ, Gibson G, Mohacsi P, Hajduczok AG, Tchantchaleishvili V, Wieselthaler G, Rame JE, Caliskan K., Late Right Heart Failure After Left Ventricular Assist Device Implantation: Contemporary Insights and Future Perspectives. JACC Heart Fail. 2023 Aug;11(8 Pt 1):865-878. doi: 10.1016/j.jchf.2023.04.014. Epub 2023 May 31.
Abdelshafy M, Caliskan K, Simpkin AJ, Elkoumy A, Kimman JR, Elsherbini H, Elzomor H, de By TMMH, Gollmann-Tepeköylü C, Berchtold-Herz M, Loforte A, Reineke D, Schoenrath F, Paluszkiewicz L, Gummert J, Mohacsi P, Meyns B, Soliman O., Efficacy of levosimendan infusion in patients undergoing a left ventricular assist device implant in a propensity score matched analysis of the EUROMACS registry-the Euro LEVO-LVAD study, Eur J Cardiothorac Surg. 2023 May 2;63(5):ezad095. doi: 10.1093/ejcts/ezad095.
Tie H, Zhu J, Akin S, Allen LA, Huang B, Martens S, Welp H, Simpkin A, Shi R, Wu Q, Soliman O, Caliskan K, Chen D., Characteristics and Outcome of Patients With a History of Cancer Undergoing Durable Left Ventricular Assist Device Implantation. Circ Heart Fail. 2023 Feb;16(2):e009772. doi: 10.1161/CIRCHEARTFAILURE.122.009772. Epub 2022 Nov 14.
Abdelshafy M, Elsherbini H, Elkoumy A, Simpkin AJ, Elzomor H, Caliskan K, Soliman O., Perioperative Levosimendan Infusion in Patients With End-Stage Heart Failure Undergoing Left Ventricular Assist Device Implantation, Front Cardiovasc Med. 2022 Apr 28;9:888136. doi: 10.3389/fcvm.2022.888136. eCollection 2022.
Abdelshafy M, Caliskan K, Guven G, Elkoumy A, Elsherbini H, Elzomor H, Tenekecioglu E, Akin S, Soliman O., Temporary Right-Ventricular Assist Devices: A Systematic Review. J Clin Med. 2022 Jan 26;11(3):613. doi: 10.3390/jcm11030613.
Bowen DJ, Yalcin YC, Strachinaru M, McGhie JS, van den Bosch AE, Soliman OI, Caliskan K., Right ventricular functional assessment by 2D multi-plane echocardiography prior to left ventricular assist device implantation. Echocardiography. 2022 Jan;39(1):7-19. doi: 10.1111/echo.15191. Epub 2021 Dec 8.
Veen KM, Mokhles MM, Soliman O, de By TMMH, Mohacsi P, Schoenrath F, Paluszkiewicz L, Netuka I, Bogers AJJC, Takkenberg JJM, Caliskan K; EUROMACS Investigators., Clinical impact and 'natural' course of uncorrected tricuspid regurgitation after implantation of a left ventricular assist device: an analysis of the European Registry for Patients with Mechanical Circulatory Support (EUROMACS). Eur J Cardiothorac Surg. 2021 Jan 4;59(1):207-216. doi: 10.1093/ejcts/ezaa294.
Akin S, Soliman O, de By TMMH, Muslem R, Tijssen JGP, Schoenrath F, Meyns B, Gummert JF, Mohacsi P, Caliskan K; EUROMACS investigators. Causes and predictors of early mortality in patients treated with left ventricular assist device implantation in the European Registry of Mechanical Circulatory Support (EUROMACS). Intensive Care Med. 2020 Jul;46(7):1349-1360. doi: 10.1007/s00134-020-05939-1. Epub 2020 Feb 3.
Yalcin YC, Muslem R, Veen KM, Soliman OI, Hesselink DA, Constantinescu AA, Brugts JJ, Manintveld OC, Fudim M, Russell SD, Tomashitis B, Houston BA, Hsu S, Tedford RJ, Bogers AJJC, Caliskan K., Impact of Continuous Flow Left Ventricular Assist Device Therapy on Chronic Kidney Disease: A Longitudinal Multicenter Study. J Card Fail. 2020 Apr;26(4):333-341. doi: 10.1016/j.cardfail.2020.01.010. Epub 2020 Jan 23.